About RNA Leaders Europe Congress:
Driving Innovation of RNA Therapeutics and Vaccines and Building New Partnerships.
Advancing Off-Target Prediction with Explainable AI.
Presentation given by Disa Tehler, Abzu’s Head of RNA Therapeutics at RNA Leaders Europe 2025 in Basel.
Disa’s presentation showcases our recent work in applying AI to predict off-target effects using RNA sequencing data.
We cover how our AI-driven method for selecting siRNA candidates offers a significant departure from traditional off-target filtering methods, leading to more effective and precisely tailored drug design strategies.
Finally, we explore how getting accurate in silico predictions can play a vital role in efficient and ethical drug development by:
- Minimizing animal experimentation.
- Contributing to a more efficient drug discovery pipeline.
- Providing clear, understandable reasons behind the selections.
At Abzu, explainable AI has been the cornerstone of our in silico drug design methodology. We have been continuously developing and improving our innovative models to predict a wide range of essential drug properties.
Missed the presentation? Download it here.
If you were unable to attend Disa’s talk or would like to revisit the information, you can download the slide deck for the presentation by filling out the form below.

Connecting with the RNA therapeutics community.
Disa, Martin Kerr (BD & Sales) and Victor Galindo (CEO) had the pleasure of connecting with researchers, industry professionals, and potential collaborators over the three days at RNA Leaders.
We thank everyone we engaged with for insightful discussions about the latest advancements and challenges in RNA therapeutics.

Reflecting on RNA Leaders 2025.
We are energized by the innovation and enthusiasm within the RNA therapeutics community present at RNA Leaders 2025 in Basel.
We believe that our explainable AI approach continues to hold significant promise for accelerating the development of safer and more effective RNA-based medicines.
Thank you to everyone who attended Disa’s presentation and engaged with our team. We look forward to continuing these important conversations and collaborations.